Number: 449 antibiotics ineffectiveness <desc> Description: What has caused the current ineffectiveness of antibiotics against infections and what is the prognosis for new drugs? <narr> Narrative: To be relevant, a document must discuss the reasons or causes for the ineffectiveness of current antibiotics. Relevant documents may also include efforts by pharmaceutical companies and federal government agencies to find new cures, updating current testing phases, new drugs being tested, and the prognosis for the availability of new and effective antibiotics.